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Diabetes and hyper-insulinemia as predictors of colorectal cancer risk in a prospective cohort of women:

Women with diabetes are 1.5 times more likely to develop colorectal cancer than those who did not have metabolic disorders, according to researchers at the University of Minnesota. The findings, they say, add to the complex body of evidence linking diet and colorectal cancer and also provide new evidence that furthers our understanding of the role of insulin in the promotion of cancer.

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"Colorectal cancer and type II diabetes share a number of common factors, including obesity, so it will be interesting to see the direct line between the two conditions," said Andrew Flood, Ph.. D., assistant professor in the Division of Epidemiology and Community Health at the University of Minnesota School of Public Health and the University of Minnesota Cancer Center "In general, the idea is that high insulin levels create a biochemical environment conducive cancer growth, it provides a mechanism by which diet and lifestyle can really influence cancer risk. "

With funding from the National Cancer Institute, Flood and his colleagues examined data from a massive screening study called the Breast Cancer Detection Demonstration Project, initiated at 29 centers across the United States in the 1970s.

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